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About

Clinical-stage biotech developing oral small molecule drugs targeting G protein-coupled receptors, including oral GLP-1 agonists for obesity treatment.

Weight Loss Stocks

Structure Therapeutics is developing oral small molecule GLP-1 drugs that could provide a more convenient alternative to injectable weight loss treatments, offering pipeline-stage obesity drug exposure.

Key Financials GPCR

Price $70.07
Change (1D) -2.73%
Change (30D) +0.75%
Change (60D) +87.15%
Change (90D) +144.32%
Change (180D) +215.63%
Change (1Y) +188.00%
P/E Ratio -52.68
EPS (TTM) $-1.33
52-Week Range $13.22 — $94.90
50-Day MA $72.42
Volume 1.25M

Data updated Feb 15 · Source: Twelve Data

4.2 1 vote

AI Reviews

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4.2 /5

Structure Therapeutics (GPCR) is a clinical-stage biotech focused on GPCR-targeted small molecule therapies, with its lead oral GLP-1 receptor agonist positioning it squarely in the booming weight loss and obesity treatment market. The stock has been a standout performer, surging over 215% in six months and 188% year-over-year, driven by promising clinical data for its oral obesity candidate that could compete with injectable GLP-1 therapies from Novo Nordisk and Eli Lilly.

The bull case centers on the massive unmet demand for convenient oral obesity treatments and Structure's differentiated small-molecule approach, which could offer manufacturing and cost advantages over peptide-based competitors. The 87% gain over 60 days reflects growing investor conviction in the pipeline.

However, significant risks remain. The company is pre-revenue with a negative EPS of -$1.33 and no P/E support, meaning valuation is entirely speculative. Clinical trial setbacks could devastate the stock. Trading roughly 26% below its 52-week high suggests some profit-taking, and competition in the oral GLP-1 space is intensifying rapidly. This is a high-risk, high-reward play best suited for investors with strong conviction in the obesity therapeutics thesis and tolerance for volatility.

Category Ratings

Weight Loss Stocks
4.2
Feb 15, 2026
AI-Generated Review Generated via Anthropic API. This is an automated evaluation, not a consumer review. Learn more
Structure Therapeutics Screenshot

Added: Feb 15, 2026

structuretx.com